Which view is used to image the maximum tissue by applying the mobile-fixed tissue principle?

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Maximizing tissue visualization in a single exposure comes from selecting a projection that brings the greatest amount of breast tissue into the beam. The Mediolateral Oblique (MLO) view is the key here, because it's angled to include the axillary tail and the posterior portions of the breast. When the medial portion of the breast is positioned toward the detector in this view, the thickest, most glandular tissue sits in the imaging field, giving the most complete picture of tissue in one image. This aligns with the idea of moving the tissue that can shift toward the detector so the major tissue mass remains within the beam. Other placements—such as inferior or superior tissue on a CC view, or lateral tissue on the MLO—tend to miss portions of tissue, especially toward the chest wall or posterior areas, and thus image less tissue overall.