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Multiple Choice

What do BI-RADS 4 and 5 indicate?

In BI-RADS, categories 4 and 5 both signal a need for tissue diagnosis. Category 4 is labeled suspicious for malignancy, so a biopsy is recommended to determine whether cancer is present (it has subcategories 4A, 4B, 4C that reflect increasing risk). Category 5 is highly suggestive of malignancy, with biopsy strongly recommended to confirm cancer and guide treatment. The key point is that both indicate enough concern to warrant sampling, whereas benign, negative, or follow-up-only scenarios do not fit these categories.

In BI-RADS, categories 4 and 5 both signal a need for tissue diagnosis. Category 4 is labeled suspicious for malignancy, so a biopsy is recommended to determine whether cancer is present (it has subcategories 4A, 4B, 4C that reflect increasing risk). Category 5 is highly suggestive of malignancy, with biopsy strongly recommended to confirm cancer and guide treatment. The key point is that both indicate enough concern to warrant sampling, whereas benign, negative, or follow-up-only scenarios do not fit these categories.