What determines spatial resolution in digital mammography with respect to pixel size?

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Spatial resolution in digital mammography is determined by how finely the image is sampled by the detector grid. The size of each pixel sets the sampling interval; smaller pixels provide more sampling points per area, allowing the system to distinguish finer structures. In other words, reducing pixel size increases the potential spatial resolution because details smaller than a pixel or two would be averaged out and become indistinct. Of course, actual sharpness also depends on other factors like detector MTF, focal spot size, and motion, but the pixel size is the primary factor that sets the fundamental limit on spatial resolution. The other terms relate more to brightness, efficiency, or exposure characteristics, not the direct sampling limit that defines resolution.